{"id":24319,"date":"2025-10-28T10:45:12","date_gmt":"2025-10-28T10:45:12","guid":{"rendered":"https:\/\/cellura.io\/?p=24319"},"modified":"2025-10-28T10:45:14","modified_gmt":"2025-10-28T10:45:14","slug":"vers-une-medecine-regenerative-equitable-grace-a-la-biofabrication-intelligente-4","status":"publish","type":"post","link":"https:\/\/cellura.io\/fr\/vers-une-medecine-regenerative-equitable-grace-a-la-biofabrication-intelligente-4\/","title":{"rendered":"Vers une m\u00e9decine r\u00e9g\u00e9n\u00e9rative \u00e9quitable gr\u00e2ce \u00e0 la biofabrication intelligente"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"24319\" class=\"elementor elementor-24319 elementor-24318\" data-elementor-post-type=\"post\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-382e7f15 elementor-section-boxed elementor-section-height-default elementor-section-height-default sc_fly_static\" data-id=\"382e7f15\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-extended\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-131aeb5e sc_content_align_inherit sc_layouts_column_icons_position_left sc_fly_static\" data-id=\"131aeb5e\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-6b53292 sc_fly_static elementor-widget elementor-widget-text-editor\" data-id=\"6b53292\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h5><mark style=\"background-color: rgba(0, 0, 0, 0);\">Why ITD 2025 matters for translation<\/mark><\/h5><p><strong style=\"font-size: 17px; letter-spacing: 0.1px;\" data-start=\"382\" data-end=\"416\">Innovative Therapies Days 2025<\/strong><span style=\"font-size: 17px; letter-spacing: 0.1px;\"> (Besan\u00e7on, <\/span><strong style=\"font-size: 17px; letter-spacing: 0.1px;\" data-start=\"428\" data-end=\"444\">October 9\u201310<\/strong><span style=\"font-size: 17px; letter-spacing: 0.1px;\">) brings together scientists, clinicians, and industry leaders working to turn advanced cell and gene therapy concepts into clinical and industrial reality. With sessions dedicated to <\/span><em style=\"font-size: 17px; letter-spacing: 0.1px;\" data-start=\"628\" data-end=\"657\">Research \u2192 Proof of Concept<\/em><span style=\"font-size: 17px; letter-spacing: 0.1px;\">, <\/span><em style=\"font-size: 17px; letter-spacing: 0.1px;\" data-start=\"659\" data-end=\"675\">Proof \u2192 Clinic<\/em><span style=\"font-size: 17px; letter-spacing: 0.1px;\">, <\/span><em style=\"font-size: 17px; letter-spacing: 0.1px;\" data-start=\"677\" data-end=\"697\">Early-Stage Trials<\/em><span style=\"font-size: 17px; letter-spacing: 0.1px;\">, and <\/span><em style=\"font-size: 17px; letter-spacing: 0.1px;\" data-start=\"703\" data-end=\"728\">Scale-Up &amp; Go-to-Market<\/em><span style=\"font-size: 17px; letter-spacing: 0.1px;\">, the event is a practical forum where science meets production.<\/span><\/p><p>This year, Cellura joins the discussion to share how its technology enables a new generation of scalable, low-shear cell-culture systems that make fragile-cell manufacturing faster, safer, and more reproducible.<\/p><h5><mark style=\"background-color: rgba(0, 0, 0, 0);\">From lab to clinic \u2014 making sensitive cells scalable and reproducible<\/mark><\/h5><p data-start=\"949\" data-end=\"1066\"><span style=\"font-size: 17px; letter-spacing: 0.1px;\">Transitioning from research to clinical-grade production remains a critical bottleneck in cell therapy. Cellura directly addresses this challenge through a <\/span><strong style=\"font-size: 17px; letter-spacing: 0.1px;\" data-start=\"1246\" data-end=\"1290\">geo-inspired, patented mixing technology<\/strong><span style=\"font-size: 17px; letter-spacing: 0.1px;\"> that mimics the Earth\u2019s rotation to generate <\/span><strong style=\"font-size: 17px; letter-spacing: 0.1px;\" data-start=\"1336\" data-end=\"1369\">chaotic yet ultra-gentle flow<\/strong><span style=\"font-size: 17px; letter-spacing: 0.1px;\"> \u2014 completely <\/span><strong style=\"font-size: 17px; letter-spacing: 0.1px;\" data-start=\"1383\" data-end=\"1396\">bladeless<\/strong><span style=\"font-size: 17px; letter-spacing: 0.1px;\">, maintaining <\/span><strong style=\"font-size: 17px; letter-spacing: 0.1px;\" data-start=\"1410\" data-end=\"1447\">12- to 50-fold lower shear forces<\/strong><span style=\"font-size: 17px; letter-spacing: 0.1px;\"> than conventional stirred-tank systems.<\/span><\/p><p data-start=\"1491\" data-end=\"1539\"><strong data-start=\"1491\" data-end=\"1537\">Key advantages for experts and developers:<\/strong><\/p><ul data-start=\"1540\" data-end=\"2080\"><li data-start=\"1540\" data-end=\"1650\"><p data-start=\"1542\" data-end=\"1650\"><strong data-start=\"1542\" data-end=\"1567\">Viability &amp; Function:<\/strong> protects iPSCs, immune cells, and organoids while ensuring robust proliferation.<\/p><\/li><li data-start=\"1651\" data-end=\"1763\"><p data-start=\"1653\" data-end=\"1763\"><strong data-start=\"1653\" data-end=\"1687\">Homogeneity &amp; Reproducibility:<\/strong> optimized mass transfer and uniform conditions across the culture vessel.<\/p><\/li><li data-start=\"1764\" data-end=\"1875\"><p data-start=\"1766\" data-end=\"1875\"><strong data-start=\"1766\" data-end=\"1787\">True Scalability:<\/strong> identical parameters from 125 mL to industrial volumes, preserving process integrity.<\/p><\/li><li data-start=\"1876\" data-end=\"1970\"><p data-start=\"1878\" data-end=\"1970\"><strong data-start=\"1878\" data-end=\"1894\">Flexibility:<\/strong> compatible with <strong data-start=\"1911\" data-end=\"1967\">microcarriers, aggregates, or single-cell suspension<\/strong>.<\/p><\/li><li data-start=\"1971\" data-end=\"2080\"><p data-start=\"1973\" data-end=\"2080\"><strong data-start=\"1973\" data-end=\"1997\">Ease of Integration:<\/strong> compact, incubator-ready, and GMP-friendly design that simplifies tech transfer.<\/p><\/li><\/ul><p data-start=\"2082\" data-end=\"2341\">Validated results include a <strong data-start=\"2110\" data-end=\"2167\">100-fold expansion of iPSCs in 7 days (&gt;99% stemness)<\/strong>, <strong data-start=\"2169\" data-end=\"2202\">10-fold expansion of NK cells<\/strong>, and <strong data-start=\"2208\" data-end=\"2256\">functional organoid formation within 15 days<\/strong> \u2014 illustrating the platform\u2019s versatility and reproducibility across applications.<\/p><h5>Connecting science, technology, and clinical impact<\/h5><p data-start=\"949\" data-end=\"1066\"><span style=\"font-size: 17px; letter-spacing: 0.1px;\">Among the speakers at ITD 2025 are <\/span><strong style=\"font-size: 17px; letter-spacing: 0.1px;\" data-start=\"2440\" data-end=\"2469\">Dr Sjoukje van der Stegen<\/strong><span style=\"font-size: 17px; letter-spacing: 0.1px;\"> (CZ Biohub, iPSC-derived immune cells), <\/span><strong style=\"font-size: 17px; letter-spacing: 0.1px;\" data-start=\"2510\" data-end=\"2531\">Prof Dani\u00e8le No\u00ebl<\/strong><span style=\"font-size: 17px; letter-spacing: 0.1px;\"> and <\/span><strong style=\"font-size: 17px; letter-spacing: 0.1px;\" data-start=\"2536\" data-end=\"2556\">Dr Farida Djouad<\/strong><span style=\"font-size: 17px; letter-spacing: 0.1px;\"> (IRMB, MSC-derived EVs and cartilage repair), <\/span><strong style=\"font-size: 17px; letter-spacing: 0.1px;\" data-start=\"2603\" data-end=\"2634\">Prof Dominique Farge-Bancel<\/strong><span style=\"font-size: 17px; letter-spacing: 0.1px;\"> (AP-HP, CAR-T for autoimmune diseases), <\/span><strong style=\"font-size: 17px; letter-spacing: 0.1px;\" data-start=\"2675\" data-end=\"2697\">Prof Sai Kiang Lim<\/strong><span style=\"font-size: 17px; letter-spacing: 0.1px;\"> (Paracrine Therapeutics, exosome therapy), <\/span><strong style=\"font-size: 17px; letter-spacing: 0.1px;\" data-start=\"2741\" data-end=\"2760\">Dr H\u00e9l\u00e8ne N\u00e8gre<\/strong><span style=\"font-size: 17px; letter-spacing: 0.1px;\"> (Cell for Cure by Seqens, ATMP release), <\/span><strong style=\"font-size: 17px; letter-spacing: 0.1px;\" data-start=\"2802\" data-end=\"2824\">Prof Erika Lietzan<\/strong><span style=\"font-size: 17px; letter-spacing: 0.1px;\"> (University of Missouri, ATMP regulation), <\/span><strong style=\"font-size: 17px; letter-spacing: 0.1px;\" data-start=\"2868\" data-end=\"2887\">Dr Rahul Purwar<\/strong><span style=\"font-size: 17px; letter-spacing: 0.1px;\"> (ImmunoACT, CAR-T in India), and <\/span><strong style=\"font-size: 17px; letter-spacing: 0.1px;\" data-start=\"2921\" data-end=\"2941\">Dr Claire Roddie<\/strong><span style=\"font-size: 17px; letter-spacing: 0.1px;\"> (Autolus, adult ALL).<\/span><\/p><p>Their insights mirror Cellura\u2019s mission: to build the technological bridge between <strong data-start=\"3049\" data-end=\"3112\">cell biology, bioengineering, and therapeutic manufacturing<\/strong>.<\/p><h5><mark style=\"background-color: rgba(0, 0, 0, 0);\">Meet us at Booth #22 \u2014 let\u2019s build tomorrow\u2019s cell therapies together<\/mark><\/h5><p data-start=\"3197\" data-end=\"3614\">Cellura will be present at <strong data-start=\"3224\" data-end=\"3237\">Booth #22<\/strong> in the <strong data-start=\"3245\" data-end=\"3268\">Exhibitors\u2019 Village<\/strong> throughout the event.<br data-start=\"3290\" data-end=\"3293\" \/>Our team will be pleased to welcome scientists, clinicians, and industrial partners to discuss ongoing and future collaborations. We will showcase our <strong data-start=\"3444\" data-end=\"3466\">SoftXS\u2122 bioreactor<\/strong>, share <strong data-start=\"3474\" data-end=\"3506\">live data and demonstrations<\/strong>, and explore opportunities for <strong data-start=\"3538\" data-end=\"3611\">joint scientific programs, pilot evaluations, and technology transfer<\/strong>.<\/p><p data-start=\"3616\" data-end=\"3730\">Let\u2019s connect in Besan\u00e7on \u2014 and together, make scalable, high-quality cell manufacturing a reality for patients.<\/p><p>If you would like to arrange a discussion with our team during the event, please contact us at our short <a href=\"https:\/\/cellura.io\/contact\/\">contact form<\/a>.<\/p><p>We look forward to engaging with the community at<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-b7eb38e elementor-section-boxed elementor-section-height-default elementor-section-height-default sc_fly_static\" data-id=\"b7eb38e\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-extended\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-8def332 sc_content_align_inherit sc_layouts_column_icons_position_left sc_fly_static\" data-id=\"8def332\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-8d7e9ee sc_fly_static elementor-widget elementor-widget-image\" data-id=\"8d7e9ee\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"194\" height=\"259\" src=\"https:\/\/cellura.io\/wp-content\/uploads\/2025\/09\/download-32.jpg\" class=\"attachment-large size-large wp-image-24245\" alt=\"\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>La m\u00e9decine r\u00e9g\u00e9n\u00e9rative est un domaine en \u00e9volution rapide offrant des perspectives prometteuses pour le traitement des maladies chroniques et d\u00e9g\u00e9n\u00e9ratives. Cependant, l\u2019acc\u00e8s \u00e9quitable \u00e0 ces th\u00e9rapies innovantes reste un&hellip;<\/p>\n","protected":false},"author":2,"featured_media":24323,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"content-type":"","footnotes":""},"categories":[217,289],"tags":[292,346,355,354,347],"class_list":["post-24319","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-laboratoire","category-research","tag-bioproduction-fr","tag-gmp-compliance-fr","tag-medecine-regenerative-fr","tag-microcarriers-fr","tag-regenerative-medicine-fr"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.4 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Vers une m\u00e9decine r\u00e9g\u00e9n\u00e9rative \u00e9quitable gr\u00e2ce \u00e0 la biofabrication intelligente - Cellura<\/title>\n<meta name=\"description\" content=\"La biofabrication intelligente et l\u2019IA rendent la m\u00e9decine r\u00e9g\u00e9n\u00e9rative plus accessible en r\u00e9duisant les co\u00fbts et en am\u00e9liorant l\u2019\u00e9quit\u00e9 des soins de sant\u00e9 \u00e0 l\u2019\u00e9chelle mondiale.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/cellura.io\/fr\/vers-une-medecine-regenerative-equitable-grace-a-la-biofabrication-intelligente-4\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Vers une m\u00e9decine r\u00e9g\u00e9n\u00e9rative \u00e9quitable gr\u00e2ce \u00e0 la biofabrication intelligente - 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